hrp0089p2-p355 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology P2 | ESPE2018

Adiponectin as a Marker of Peripheral Insulin Resistance in Adolescents with Polycystic Ovarian Syndrome (PCOS) and as a Tool to Suspect Insulin Receptor Defects

Freire Analia , Gryngarten Mirta , Ballerini Maria Gabriela , Arcari Andrea , Bengolea Sonia Viviana , Scaglia Paula , Bergada Ignacio , Ropelato Maria Gabriela

Background: Decreased serum adiponectin levels are associated with obesity and peripheral insulin resistance (IR). PCOS is characterized by hyperandrogenism and chronic anovulation and frequently is associated to IR. Some defects of Insulin Receptor have been proposed as mechanisms to explain ovarian hyperandrogenism in PCOS.Objectives: To explore adiponectin levels in adolescents with PCOS and to evaluate if adiponectin would identify potential patients...